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PRECLINICAL PUBLICATION · 2018

Traumatic Brain Injury Disrupts Pain Signaling in the Brainstem and Spinal Cord.

Rat / TBI

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 29373948 ↗2018Mixed findings

Traumatic Brain Injury Disrupts Pain Signaling in the Brainstem and Spinal Cord.

RatTBIFluid percussionLong-EvansMaleAdministered for several days after traumatic brain injury

Model: Lateral fluid percussion traumatic brain injury

Traumatic brain injury caused transient mechanical allodynia and chronic loss of diffuse noxious inhibitory control; anacardic acid blocked acute nociceptive sensitisation and some early neuropathology but did not prevent loss of diffuse noxious inhibitory control or long-term neuropathological cha…

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.