THERAPY DOSSIER · th-571357b588e5

Anacardic acid

Drug

Evidence & regulatory context

Mechanism: Not recorded
Target: Not recorded
Injury models: TBI
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 0

0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

No linked human trial in this dataset.

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 29373948 ↗2018Mixed findings

Traumatic Brain Injury Disrupts Pain Signaling in the Brainstem and Spinal Cord.

RatTBIFluid percussionLong-EvansMaleAdministered for several days after traumatic brain injury

Model: Lateral fluid percussion traumatic brain injury

Traumatic brain injury caused transient mechanical allodynia and chronic loss of diffuse noxious inhibitory control; anacardic acid blocked acute nociceptive sensitisation and some early neuropathology but did not prevent loss of diffuse noxious inhibitory control or long-term neuropathological cha…

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.

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