Brain repair by hematopoietic growth factors in the subacute phase of traumatic brain injury.
MouseTBIUnspecifiedC57BLMaleSubcutaneous injectionSCF 200 micrograms/kg and G-CSF 50 micrograms/kg, or equal…Treatment initiated 2 weeks after traumatic brain injury
Model: Traumatic brain injury to the cortex of the right hemisphere
Combined SCF and G-CSF restored spatial learning and memory, reduced anxiety and risk-taking behaviour, lowered neurodegeneration in the contralateral hemisphere and increased frontal cortical dendritic density, with no effect on motor function or object recognition.
Extraction: extract · Supplied extraction confidence: 0.72. Machine-extracted fields require source verification.