Biologic
1 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.
Childhood Acute Lymphoblastic Leukemia in Remission · Childhood Acute Myeloid Leukemia in Remission
Enrolment: 27 · Results not recorded
Myasthenia Gravis
Enrolment: 9 · Results not recorded
Acute Leukemia in Remission · Myelodysplastic Syndromes
Enrolment: 32 · Results not recorded
Beta Thalassemia Major · Congenital Anemias
Enrolment: 5 · Results not recorded
3 studies reported at therapy level; 3 evidence entries itemised.
Model: Controlled cortical impact causing severe damage to the motor cortex of the right hemisphere
Combined SCF and G-CSF started 3 weeks post-injury significantly improved impaired spatial learning at 6 weeks after treatment, reduced neurodegeneration in contralateral frontal cortex and hippocampal CA1, increased MAP2 apical dendrites in peri-injury cortex and prevented axonal overgrowth, but m…
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.
Model: Traumatic brain injury to the cortex of the right hemisphere
Combined SCF and G-CSF restored spatial learning and memory, reduced anxiety and risk-taking behaviour, lowered neurodegeneration in the contralateral hemisphere and increased frontal cortical dendritic density, with no effect on motor function or object recognition.
Extraction: extract · Supplied extraction confidence: 0.72. Machine-extracted fields require source verification.
Model: Renal ischaemia-reperfusion injury with acute tubular necrosis in rats
Combined SCF and G-CSF increased bone marrow stem cell numbers in damaged kidney and reduced the degree of renal tissue damage, with higher HIF-1 alpha, VEGF and erythropoietin expression than in other groups.
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.65. Machine-extracted fields require source verification.
