Hyperbaric oxygen reduces inflammation, oxygenates injured muscle, and regenerates skeletal muscle via macrophage and satellite cell activation.
RatCrushLimb / muscle crushWistarMalen = Approximately 400 rats in total; per assay n = 5 to 20 depe…Inhalation in a hyperbaric chamber100% oxygen at 2.5 atmospheres absolute for 2 hours (15 min…First treatment about 15 minutes after contusion
Model: Calf muscle contusion by modified mass-drop method; 640 g aluminium cylinder dropped from 250 mm onto a 10 mm hemispherical impactor over the medial calf
Hyperbaric oxygen improved tissue oxygenation, reduced early limb volume, wet weight and vascular permeability, increased regenerating myofibres and isometric strength at day 7, and shifted macrophage and satellite cell kinetics earlier via IL-6/STAT3.
Extraction: extract · Subtype source: llm · Supplied extraction confidence: 0.9. Machine-extracted fields require source verification.