Grafts of Olfactory Stem Cells Restore Breathing and Motor Functions after Rat Spinal Cord Injury.
RatSpinal cord injuryContusionInbred F344Intraspinal transplantation into the injured spinal cordDelayed transplantation two days after contusion
Model: Acute high cervical contusion spinal cord injury causing persistent hemidiaphragmatic and foreleg paralysis
Grafting improved breathing movements, ipsilateral phrenic nerve and diaphragm activity and locomotor ability at four months, with reduced axonal disorganisation and inflammation and some grafted cells adopting a neuronal phenotype.
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.68. Machine-extracted fields require source verification.