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← Studies/PMID 29357041
PRECLINICAL PUBLICATION · 2018

Resolvin D1 Halts Remote Neuroinflammation and Improves Functional Recovery after Focal Brain Damage Via ALX/FPR2 Receptor-Regulated MicroRNAs.

Rat / Other

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Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 29357041 ↗2018Reported benefit

Resolvin D1 Halts Remote Neuroinflammation and Improves Functional Recovery after Focal Brain Damage Via ALX/FPR2 Receptor-Regulated MicroRNAs.

RatOtherWistarMaleIn vivo administration; ALX/FPR2 neutralisation given intracerebroventricularlyAfter hemicerebellectomy

Model: Hemicerebellectomy, a model of focal brain injury with remote secondary damage

Resolvin D1 promoted functional recovery and neuroprotection by reducing microglial and astrocytic activation and inflammation-driven neuronal death in remote regions, effects reversed by ALX/FPR2 neutralisation.

Extraction: extract · Supplied extraction confidence: 0.62. Machine-extracted fields require source verification.