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PRECLINICAL PUBLICATION · 2018

Protective effects of Artemisia campestris extract against gastric acid reflux-induced esophageal mucosa injuries.

Rat / Other

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 29306510 ↗2018Reported benefit

Protective effects of Artemisia campestris extract against gastric acid reflux-induced esophageal mucosa injuries.

RatOtherOral (per os)100, 200 and 400 mg/kg body weight

Model: Gastro-oesophageal reflux-induced oesophagitis produced by ligation of the pylorus and of the junction between the forestomach and the corpus

The aqueous extract dose-dependently reduced macroscopic and histological oesophageal injury and lipid peroxidation, and restored antioxidant enzyme activities and intracellular mediator levels.

Extraction: extract · Supplied extraction confidence: 0.65. Machine-extracted fields require source verification.