Protective effects of Artemisia campestris extract against gastric acid reflux-induced esophageal mucosa injuries.
RatOtherOral (per os)100, 200 and 400 mg/kg body weight
Model: Gastro-oesophageal reflux-induced oesophagitis produced by ligation of the pylorus and of the junction between the forestomach and the corpus
The aqueous extract dose-dependently reduced macroscopic and histological oesophageal injury and lipid peroxidation, and restored antioxidant enzyme activities and intracellular mediator levels.
Extraction: extract · Supplied extraction confidence: 0.65. Machine-extracted fields require source verification.