Thermal skin injury: I. Acute hemodynamic effects of fluid resuscitation with lactated Ringer's, plasma, and hypertonic saline (2,400 mosmol/l) in the rat.
RatBurnScaldInbred strain not specifiedFemaleIntravenousLactated Ringer's 5 ml/h; plasma 2.5 ml/h; hypertonic salin…Postburn
Model: 40% total body surface area full-thickness scald burn under anaesthesia
Cardiac index fell to 58-71% of control within 15 min of burn. Lactated Ringer's and plasma raised cardiac index to 74-80% of control and prevented the fall in mean arterial pressure seen in untreated burns (110 to 80 mmHg at 3 h), and limited haemoconcentration (haematocrit 48 to 52% versus 48 to…
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