Effect of injury-curing cataplasma on expression of AQP3 in skeletal muscles of rats by regulating cAMP-PKA signal pathway.
RatOtherSprague-DawleyMalen = 48 rats (three groups of 16)Topical (local application fixed with tape)Applied after injury induction
Model: Acute closed soft tissue (skeletal muscle) injury model in the depilated dorsal region
Treated rats showed higher AQP3 and PKA and lower PGE2 and cAMP than injured controls at 3, 7 and 14 days (P<0.01), consistent with promotion of swelling resolution via the cAMP-PKA pathway
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