THERAPY DOSSIER · th-919b04f6f4bd

Injury-curing cataplasma (Chinese herbal topical preparation)

Nutraceutical

Evidence & regulatory context

Mechanism: Not recorded
Target: Not recorded
Injury models: Other
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 0

0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

No linked human trial in this dataset.

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 29084662 ↗2017Reported benefit

Effect of injury-curing cataplasma on expression of AQP3 in skeletal muscles of rats by regulating cAMP-PKA signal pathway.

RatOtherSprague-DawleyMalen = 48 rats (three groups of 16)Topical (local application fixed with tape)Applied after injury induction

Model: Acute closed soft tissue (skeletal muscle) injury model in the depilated dorsal region

Treated rats showed higher AQP3 and PKA and lower PGE2 and cAMP than injured controls at 3, 7 and 14 days (P<0.01), consistent with promotion of swelling resolution via the cAMP-PKA pathway

Extraction: extract · Supplied extraction confidence: 0.5. Machine-extracted fields require source verification.

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