Nacre-mimic Reinforced Ag@reduced Graphene Oxide-Sodium Alginate Composite Film for Wound Healing.
RatWoundSprague-Dawleymalen = 5 rats, each carrying one treated and one control woundTopical, applied as a wound dressingComposite film containing 20% (w/w) Ag@rGO, approximately 3…Applied immediately after wound creation
Model: Two round full-thickness excisional skin wounds of about 0.5 cm diameter cut in depilated dorsal hip skin, one on each side of each rat
Wound area was reduced by 19.4%, 79.5% and 92% at days 3, 5 and 7 in the AGSA film group compared with 13.8%, 39.3% and 51.5% in the standard treatment control. Histology showed fewer inflammatory cells and more compact, better ordered collagen bundles with AGSA. Inhibition zones were 1.30, 0.65 an…
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