THERAPY DOSSIER · th-36970005d661

Ag@reduced graphene oxide-sodium alginate (AGSA) composite film

Device

Evidence & regulatory context

Mechanism: Not recorded
Target: Not recorded
Injury models: Wound
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 0

0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

No linked human trial in this dataset.

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 29062048 ↗2017Reported benefit

Nacre-mimic Reinforced Ag@reduced Graphene Oxide-Sodium Alginate Composite Film for Wound Healing.

RatWoundSprague-Dawleymalen = 5 rats, each carrying one treated and one control woundTopical, applied as a wound dressingComposite film containing 20% (w/w) Ag@rGO, approximately 3…Applied immediately after wound creation

Model: Two round full-thickness excisional skin wounds of about 0.5 cm diameter cut in depilated dorsal hip skin, one on each side of each rat

Wound area was reduced by 19.4%, 79.5% and 92% at days 3, 5 and 7 in the AGSA film group compared with 13.8%, 39.3% and 51.5% in the standard treatment control. Histology showed fewer inflammatory cells and more compact, better ordered collagen bundles with AGSA. Inhibition zones were 1.30, 0.65 an…

Extraction: extract · Supplied extraction confidence: 0.9. Machine-extracted fields require source verification.

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