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PRECLINICAL PUBLICATION · 2018

Effects of Copaiba oil in the healing process of urinary bladder in rats.

Rat / Wound

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 29039895 ↗2018Mixed findings

Effects of Copaiba oil in the healing process of urinary bladder in rats.

RatWoundWistarmalen = 10 rats, 5 per groupTopical, injected directly onto the bladder suture line0.63 mL/kg per the abstract; the methods section of the ful…Immediately after closure of the cystotomy

Model: Laparotomy with 1 cm cystotomy of the urinary bladder closed with 4-0 polydioxanone suture

Adhesion formation did not differ between groups (p=0.1481). Copaiba oil significantly increased foreign-body giant cell reaction and vascular proliferation (both p=0.047) but did not alter acute inflammation, necrosis, fibroblast number, collagen grade or re-epithelialisation. Collagen volumetric…

Extraction: extract · Supplied extraction confidence: 0.85. Machine-extracted fields require source verification.