Gelatin promotes rapid restoration of the blood brain barrier after acute brain injury.
RatTBIPenetrating / ballisticSprague-DawleyFemaleLocal (coating on the inserted needle)At the moment of injury (coated needle insertion)
Model: Transient insertion of stainless steel needles into cortex cerebri (stab wound mimicking neural implant injury)
Gelatin-coated needle injuries showed significantly faster resolution of post-stab bleeding and BBB leakage, differential microglial responses and later increases in MMP-2 and MMP-9, with neurons and astrocytes largely unaffected
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.