PebbleAtlas
PEBBLE / ATLAS
Open research access
PRECLINICAL PUBLICATION · 2017

Quercetin reduces neural tissue damage and promotes astrocyte activation after spinal cord injury in rats.

Rat / Spinal cord injury

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 28865131 ↗2017Reported benefit

Quercetin reduces neural tissue damage and promotes astrocyte activation after spinal cord injury in rats.

RatSpinal cord injuryContusionSprague-DawleyIntraperitoneal20 mg/kgCommenced after injury and laminectomy

Model: Spinal cord injury at T10 produced by the modified Allen weight-drop method following laminectomy

Quercetin improved locomotor and electrophysiological recovery, reduced cavity formation, and promoted astrocyte activation and axonal regeneration after acute spinal cord injury, with increased BDNF and reduced phosphorylated JNK2 and STAT3.

Extraction: extract · Subtype source: llm · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.