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PRECLINICAL PUBLICATION · 2017

Systemic Neutrophil Depletion Modulates the Migration and Fate of Transplanted Human Neural Stem Cells to Rescue Functional Repair.

Mouse / Spinal cord injury

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 28847814 ↗2017Mixed findings

Systemic Neutrophil Depletion Modulates the Migration and Fate of Transplanted Human Neural Stem Cells to Rescue Functional Repair.

MouseSpinal cord injuryUnspecifiedFemaleAcute transplantation at 0 days post-injury, compared with previously reported…

Model: Spinal cord injury in an immunodeficient mouse model

Acute transplantation at 0 days post-injury produced localised astroglial differentiation near the lesion epicentre and failed to improve locomotor function, whereas specific immunodepletion of neutrophils with anti-Ly6G blocked astroglial differentiation and rescued the capacity of the transplante…

Extraction: extract · Supplied extraction confidence: 0.65. Machine-extracted fields require source verification.