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PRECLINICAL PUBLICATION · 2017

A Study of the Therapeutic Effects of Resveratrol on Blunt Chest Trauma-Induced Acute Lung Injury in Rats and the Potential Role of Endocan as a Biomarker of Inflammation.

Rat / Other

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 28726014 ↗2017Mixed findings

A Study of the Therapeutic Effects of Resveratrol on Blunt Chest Trauma-Induced Acute Lung Injury in Rats and the Potential Role of Endocan as a Biomarker of Inflammation.

RatOthern = n = 7 per group across four groups (28 total)Intraperitoneal0.3 mg/kgAdministered 1 hour prior to induction of trauma

Model: Blunt chest trauma-induced acute lung injury; method of trauma induction not specified in the abstract

Resveratrol increased superoxide dismutase activity and the authors concluded it exerted antioxidant properties in blunt chest trauma-induced lung injury. Serum endocan rose in all trauma and resveratrol groups and was not correlated with the inflammatory response, so the authors did not recommend…

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