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PRECLINICAL PUBLICATION · 2017

Anti-edematous, anti-inflammatory and neuroprotective effect of etanercept in acute stage in experimental head injury.

Rat / TBI

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 28530785 ↗2017Reported benefit

Anti-edematous, anti-inflammatory and neuroprotective effect of etanercept in acute stage in experimental head injury.

RatTBIPenetrating / ballisticSprague-DawleyMalen = 40 rats in total across the groupsIntraperitonealAfter trauma

Model: Non-penetrating experimental head injury

Dexamethasone differed significantly from saline only for oedema and inflammation, with no difference for neuronal damage, astrocytic damage or glial apoptosis. Etanercept differed significantly from both saline and dexamethasone across all variables, indicating anti-oedematous, anti-inflammatory a…

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.