Beneficial effects of garlic (Allium sativum) oil in experimental corrosive esophageal burns effects of garlic oil in esophageal burns.
RatBurnChemical / corrosiven = 28 rats, randomly divided into 4 equal groups of 7Topical to the burned oesophageal segment in one group; topical plus systemic administration in a second group
Model: Corrosive oesophageal burn produced by applying sodium hydroxide to a 1.5 cm segment of the abdominal oesophagus
Hydroxyproline was lower in the topical treatment groups than in controls (p = 0.023) and tumour necrosis factor alpha differed between the systemic treatment group and control (p = 0.044). Garlic oil reduced the stenosis index, significantly so in the topical group (p = 0.016), and reduced the his…
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