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PRECLINICAL PUBLICATION · 2017

Effects of Quercetin and Mannitol on Erythropoietin Levels in Rats Following Acute Severe Traumatic Brain Injury.

Rat / TBI

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 28490163 ↗2017Reported benefit

Effects of Quercetin and Mannitol on Erythropoietin Levels in Rats Following Acute Severe Traumatic Brain Injury.

RatTBIWeight-drop / impact-accelerationWistarMalen = 40 rats, 10 per groupIntravenousQuercetin 50 mg/kg; mannitol 1 mg/kg as printed in the sour…After traumatic brain injury; exact interval not stated

Model: Weight-drop impact acceleration model of acute severe traumatic brain injury; weight-drop height and mass not stated

Both quercetin and mannitol lowered malondialdehyde and raised catalase and glutathione peroxidase relative to untreated injury; mannitol significantly reduced serum erythropoietin and 4 hour haematocrit whereas quercetin did not.

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.85. Machine-extracted fields require source verification.