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PRECLINICAL PUBLICATION · 2017

E-Cadherin-Mediated Cell Contact Controls the Epidermal Damage Response in Radiation Dermatitis.

Mixed / Radiation

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 28456613 ↗2017Reported benefit

E-Cadherin-Mediated Cell Contact Controls the Epidermal Damage Response in Radiation Dermatitis.

MixedRadiationC57BL/6 mice and Sprague-Dawley ratsMale

Model: Ionising radiation-induced acute epidermal damage, radiation dermatitis, in rodent skin

Genistein and dasatinib reduced reactive oxygen species-induced degradation of beta-catenin and E-cadherin in vitro and ameliorated skin damage in rodent radiation dermatitis models.

Extraction: extract · Supplied extraction confidence: 0.65. Machine-extracted fields require source verification.