A high-glucose diet affects Achilles tendon healing in rats.
RatWoundLewisFemalen = 60 female rats in total; 2-week arm control n=24 and high-g…Oral (dietary)Diet composed of 67 kJ % carbohydrates (50.0 glucose, 12.0…Feeding regimen commenced immediately after tenotomy surgery
Model: 2 mm full-thickness transverse Achilles tenotomy of the right hind limb, tendon left unsutured
The high-glucose diet increased repair tissue thickness at 2 weeks (4.15 plus or minus 0.36 mm versus 3.55 plus or minus 0.45 mm, p less than 0.0001) and stiffness (20.8 plus or minus 8.1 versus 15.1 plus or minus 4.3 N/mm, p less than 0.05), and improved intermediate toe spread at 1 and 2 weeks. M…
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