THERAPY DOSSIER · th-c168373ef85f

High-glucose diet (ssniff EF R/M High glucose)

Nutraceutical

Evidence & regulatory context

Mechanism: Not recorded
Target: Not recorded
Injury models: Wound
Reported indication: Not recorded
First approval: Not recorded
Development stage: Not recorded
ChEMBL record: Not recorded
ChEMBL max phase: Not recorded
Synonyms: Not recorded
Note: Not recorded

Clinical trials 0

0 linked trials carry an injury-indication flag. These flags support record-level exploration and sit alongside the stringent aggregate counts described in Methods.

No linked human trial in this dataset.

Preclinical evidence 1

1 studies reported at therapy level; 1 evidence entries itemised.

PMID 28396584 ↗2017Mixed findings

A high-glucose diet affects Achilles tendon healing in rats.

RatWoundLewisFemalen = 60 female rats in total; 2-week arm control n=24 and high-g…Oral (dietary)Diet composed of 67 kJ % carbohydrates (50.0 glucose, 12.0…Feeding regimen commenced immediately after tenotomy surgery

Model: 2 mm full-thickness transverse Achilles tenotomy of the right hind limb, tendon left unsutured

The high-glucose diet increased repair tissue thickness at 2 weeks (4.15 plus or minus 0.36 mm versus 3.55 plus or minus 0.45 mm, p less than 0.0001) and stiffness (20.8 plus or minus 8.1 versus 15.1 plus or minus 4.3 N/mm, p less than 0.05), and improved intermediate toe spread at 1 and 2 weeks. M…

Extraction: extract · Supplied extraction confidence: 0.93. Machine-extracted fields require source verification.

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