Amniotic membrane as an option for treatment of acute Achilles tendon injury in rats.
RatOtherWistarMalen = 60 rats in 3 groups, subdivided across 4 time pointsLocal application to the injured tendonAt the time of the surgical tendon injury
Model: Surgical acute Achilles tendon injury
Tendons treated with human amniotic membrane showed better collagen fibre alignment at 14 days and features of mature connective tissue at 28 days, with reduced inflammatory response and intense fibroblast proliferation compared with untreated injured tendons. FTIR distinguished all three groups at…
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