Effect of Fibrin Packing on Managing Hepatic Hemorrhage and Liver Wound Healing in a Model of Liver Stab Wound in Rat.
RatWoundSprague DawleyMalen = 20 adult male rats in two groupsTopical perihepatic packingApplied at the time of the stab wound during surgery
Model: Liver stab wound created with a number 15 scalpel cutting bilateral liver capsules and liver tissue, producing acute bleeding
Estimated blood loss was 2.89 plus or minus 0.73 mL with fibrin packing versus 4.98 plus or minus 0.77 mL with gauze packing (p < 0.001). Mortality was 0% versus 50% within 12 h. ALT and AST returned to normal in 4 days versus 6 days and haematocrit recovered by 48 h versus 72 h. Total serum biliru…
Extraction: extract · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.