Eff ects of hemin, a heme oxygenase-1 inducer in L-arginine-induced acute pancreatitis and associated lung injury in adult male albino rats.
RatChemical/toxinAlbino (indexed as Sprague-Dawley in MeSH terms)Malen = 24 adult male rats in four groupsOne group pre-treated before induction of pancreatitis and one group post-treat…
Model: L-arginine-induced acute pancreatitis with associated lung injury
Hemin given before induction significantly attenuated the rise in serum amylase, lipase, tumour necrosis factor alpha and nitric oxide, compensated the deficit in total antioxidant capacity, lowered malondialdehyde and improved pancreatic and pulmonary histology. Hemin given after induction showed…
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