PebbleAtlas
PEBBLE / ATLAS
Open research access
PRECLINICAL PUBLICATION · 2017

Effects of NO Synthase Blocker L-NAME on Functional State of the Neuromotor System during Traumatic Disease of the Spinal Cord.

Rat / Spinal cord injury

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 28091928 ↗2017Outcome unclear

Effects of NO Synthase Blocker L-NAME on Functional State of the Neuromotor System during Traumatic Disease of the Spinal Cord.

RatSpinal cord injuryContusionOutbredMale and femaleAcute period after spinal cord injury; timing selected from electron paramagnet…

Model: Experimental contusion injury of the spinal cord

L-NAME given during the acute period after spinal cord contusion sharply reduced the intensity of evoked motor responses and produced a more pronounced increase in excitability of peripheral motor structures. The authors interpret this as evidence that the nitric oxide system regulates stress-induc…

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.5. Machine-extracted fields require source verification.