PebbleAtlas
PEBBLE / ATLAS
Open research access
PRECLINICAL PUBLICATION · 1989

Dependence between the free-radical peroxidation, the activity of the superoxide dismutase glucose-6-phosphate dehydrogenase and erythrocytes haemolysis after thermal trauma and alpha-tocopherol treatment.

Rat / Burn

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 2801150 ↗1989Reported benefit

Dependence between the free-radical peroxidation, the activity of the superoxide dismutase glucose-6-phosphate dehydrogenase and erythrocytes haemolysis after thermal trauma and alpha-tocopherol treatment.

RatBurnUnspecifiedWistarMaleIntraperitoneal20 mg/kg body massAfter thermal trauma

Model: Grade IIIa-IIIb thermal burn over 15-20% of body surface

Free-radical oxidation products and erythrocyte haemolysis rose in parallel after burn injury. Alpha-tocopherol reduced free-radical oxidation products and increased antioxidative protection and erythrocyte resistance during the acute postburn period.

Extraction: extract · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.