Sulphoraphane Improves Neuronal Mitochondrial Function in Brain Tissue in Acute Carbon Monoxide Poisoning Rats.
RatChemical/toxinSprague-DawleyMaleEarly administration after carbon monoxide exposure; exact interval not stated
Model: Acute carbon monoxide poisoning by exposure to carbon monoxide, with hippocampal neuronal mitochondrial injury and cognitive dysfunction
Carbon monoxide poisoning induced cognitive dysfunction, seriously damaged neuronal mitochondrial ultrastructure, reduced mitochondrial membrane potential and increased Nrf-2 and Trx-1 protein and mRNA. Early administration of middle-dose or high-dose sulphoraphane efficiently improved mitochondria…
Extraction: extract · Supplied extraction confidence: 0.6. Machine-extracted fields require source verification.