Acute inflammatory response of the rat pawskin to acid injury is attenuated by corticotropin-releasing factor.
RatBurnScaldMaleIntravenous28 micrograms/kg10 min before acid immersion
Model: Chemical burn produced by 2 min immersion of the paw in 12 N hydrochloric, 18 N sulfuric or 14 N hydrofluoric acid
Corticotropin-releasing factor given before acid immersion reduced skin weight gain and Evans blue extravasation, indicating attenuation of the acute inflammatory increase in vascular permeability.
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.85. Machine-extracted fields require source verification.