Sesame oil improves functional recovery by attenuating nerve oxidative stress in a mouse model of acute peripheral nerve injury: role of Nrf-2.
MouseCrushPeripheral-nerve crushC57BL/6 (inbred C57BL)Malen = 30 mice in total, 5 groups of 6Oral ingestion0.5, 1 or 2 mL/kg per dayDaily from the day of sciatic nerve crush
Model: Sciatic nerve crush
Sesame oil significantly reduced lipid peroxidation and increased nuclear Nrf2 and GAP43 expression in the injured sciatic nerve, and improved electrophysiological and functional recovery after crush injury.
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.8. Machine-extracted fields require source verification.