Early care of acute hyperglycemia benefits the outcome of traumatic brain injury in rats.
RatTBIControlled cortical impactSprague-DawleyMaleEarly after injury
Model: Controlled cortical impact traumatic brain injury with strike depths of 3.0 to 4.25 mm at right or left occipitoparietal or frontoparietal regions
Only severe impact (3.5 to 4.25 mm) induced acute hyperglycaemia lasting up to 24 h with reduced insulin sensitivity and secretion for 72 h, and intervention for acute hyperglycaemia lowered the modified neurological severity score from 2 to 7 days after injury.
Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.5. Machine-extracted fields require source verification.