Melatonin: is it an effective antioxidant for pulmonary contusion?
RatOtherSprague-DawleyMalen = 49 rats across three groupsIntraperitonealAfter trauma
Model: Pulmonary contusion induced by isolated blunt thoracic trauma
On day 2 melatonin lowered malondialdehyde and total oxidant capacity, raised total antioxidant capacity, improved blood gases and liver and kidney biochemistry, and reduced histological damage scores relative to untreated trauma.
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