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PRECLINICAL PUBLICATION · 2016

Transplantation of Pro-Oligodendroblasts, Preconditioned by LPS-Stimulated Microglia, Promotes Recovery After Acute Contusive Spinal Cord Injury.

Rat / Spinal cord injury

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 27513556 ↗2016Reported benefit

Transplantation of Pro-Oligodendroblasts, Preconditioned by LPS-Stimulated Microglia, Promotes Recovery After Acute Contusive Spinal Cord Injury.

RatSpinal cord injuryContusionWistarMaleIntrathecal delivery via lumbar punctureAfter T10 contusive spinal cord injury; exact interval not stated in the abstra…

Model: T10 thoracic contusive spinal cord injury

Transplantation of preconditioned pro-oligodendroblasts improved locomotor recovery and increased intralesional axon numbers and myelination, with less macrophage accumulation, compared with vehicle control or oligodendrocyte progenitor cell transplantation.

Extraction: extract · Subtype source: rule · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.