Functional Recovery from Neural Stem/Progenitor Cell Transplantation Combined with Treadmill Training in Mice with Chronic Spinal Cord Injury
MouseSpinal cord injuryContusionC57BL/6JFemalen = 70Intraspinal injection49 days after injury (chronic phase)
Model: 70 kdyn contusive spinal cord injury at T9
Combined transplantation and treadmill training improved locomotor score (p=0.035) and gait speed (p=0.026) relative to control, reduced spasticity and promoted neuronal differentiation of grafted cells with synaptic maturation
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