Ischemia-induced spreading depolarization in the retina.
RatIschaemia-reperfusionOther / unspecified
Model: Photothrombotic retinal vessel occlusion producing acute retinal ischaemia in vivo
Spreading depolarisation episodes were generated in the rat retina in vivo after photothrombotic vessel occlusion, propagating at 3.0 plus or minus 0.1 mm/min with a negative direct current shift, transient cessation of spiking, arteriole constriction and reduced tissue oxygen tension. Administrati…
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