Protective Effects of Intralipid and Caffeic Acid Phenethyl Ester (CAPE) on Hepatotoxicity and Pancreatic Injury Caused by Dichlorvos in Rats.
RatChemical/toxinWistarMalen = 48 rats in 7 groups, 7 rats per group except control groups
Model: Acute dichlorvos (organophosphate) intoxication causing hepatotoxicity and pancreatic injury
CAPE and intralipid raised total antioxidant status and reduced apoptotic and mitotic cell counts in liver, with pancreatic necrosis replaced by only mild congestion and oedema after treatment.
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