The Effect of Purified Human Bone Marrow-Derived Mesenchymal Stem Cells on Rotator Cuff Tendon Healing in an Athymic Rat.
RatOtherAthymic nude ratn = 52 athymic rats total; per timepoint 10 per group for biome…Local application at the tendon repair site in fibrin glueAt the time of surgical repair
Model: Unilateral detachment and transosseous repair of the supraspinatus tendon (acute small to medium rotator cuff tear and repair)
At 2 weeks human mesenchymal stem cells increased fibrocartilage formation (18.6 +/- 2.9% vs 9.1 +/- 1.6%, P = .026), improved collagen organisation (energy 36.88 +/- 4.99 J vs 54.97 +/- 8.33 J, P = .04; coherence 26.96 +/- 15.32% vs 14.53 +/- 4.10%, P = .05), and raised failure load (11.5 +/- 2.4…
Extraction: extract · Supplied extraction confidence: 0.75. Machine-extracted fields require source verification.