PebbleAtlas
PEBBLE / ATLAS
Open research access
PRECLINICAL PUBLICATION · 2016

Amygdala electrical stimulation inducing spatial memory recovery produces an increase of hippocampal bdnf and arc gene expression.

Rat / Other

Evidence by therapy association

Study details and outcomes are extracted in the context of a specific intervention. Separate associations are retained rather than silently merged.

PMID 27262671 ↗2016Reported benefit

Amygdala electrical stimulation inducing spatial memory recovery produces an increase of hippocampal bdnf and arc gene expression.

RatOtherWistarMaleImplanted electrode, direct electrical stimulation of the basolateral amygdalaApplied after fimbria-fornix lesioning, 15 min after each daily water maze trai…

Model: Bilateral fimbria-fornix lesion causing spatial memory deficit

Daily basolateral amygdala electrical stimulation 15 min after water maze training produced partial recovery of spatial memory in fimbria-fornix lesioned rats, accompanied by increased hippocampal bdnf and arc gene expression. In non-lesioned untrained animals a single stimulation session caused a…

Extraction: extract · Supplied extraction confidence: 0.65. Machine-extracted fields require source verification.