Trauma-Related Acute Lung Injury Develops Rapidly Irrespective of Resuscitation Strategy in the Rat.
RatHaemorrhage/shockUnspecifiedSprague-DawleyIntravenous resuscitationResuscitation begun 1 hour after trauma
Model: Polytrauma with haemorrhage in anaesthetised rats
Polytrauma and haemorrhage without resuscitation increased lung leukocytes, platelets, myeloperoxidase and both pro- and anti-inflammatory cytokines and chemokines. Resuscitation with Lactated Ringer, fresh whole blood or stored whole blood all raised the lung wet to dry ratio to a similar extent,…
Extraction: extract · Supplied extraction confidence: 0.7. Machine-extracted fields require source verification.