Carbon monoxide promotes gastric wound healing in mice via the protein kinase C pathway.
MouseWoundC57BL/6maleoralCO-saturated saline prepared by bubbling 50% CO gas into sa…beginning on day 3 after gastric ulcer induction
Model: acetic acid-induced gastric ulcer
Oral administration of CO-saturated saline accelerated gastric ulcer healing by promoting re-epithelialisation, and CO enhanced murine gastric epithelial cell migration in vitro through activation of protein kinase C.
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