Temporal changes in the expression of the translocator protein TSPO and the steroidogenic enzyme 5alpha-reductase in the dorsal spinal cord of animals with neuropathic pain: Effects of progesterone administration.
RatSpinal cord injuryUnspecifiedSprague-DawleyMaleInjection
Model: Spinal cord injury producing central chronic neuropathic pain, with assessment at 1, 14 and 28 days
Progesterone-treated injured rats did not develop allodynia and showed increased spinal TSPO, StAR and 5alpha-reductase I and II mRNA at 28 days after injury.
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