Naloxone pretreatment prevents kidney injury after liver ischemia reperfusion injury.
RatIschaemia-reperfusionHepaticWistarMalen = 40 rats in four groups of 10Intravenous3.0 mg/kg30 min before ischaemia
Model: Hepatic ischaemia for 30 min followed by reperfusion, with remote kidney injury assessed at 24 h
Naloxone pretreatment reduced renal and hepatic histological damage and lowered malondialdehyde levels after hepatic ischaemia-reperfusion.
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