Remote ischemic conditioning protects against acetaminophen-induced acute liver injury in mice.
MouseChemical/toxinn = n = 6 per group across seven groupsRemote ischaemic conditioningPreconditioning before and postconditioning after acetaminophen administration
Model: Acetaminophen overdose-induced acute liver injury
Both preconditioning and postconditioning significantly lowered transaminases, pro-inflammatory cytokines and oxidative markers and raised antioxidant enzyme activity and haem oxygenase-1; zinc protoporphyrin abolished the protection.
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