Effects of lidocaine on torn rotator cuff tendons.
RatOtherSprague-DawleyIntra-articular subacromial shoulder injection0.1 per cent lidocaine used in vitro; injected volume and c…Injected at the time of surgery before wound closure
Model: Surgically created acute supraspinatus tendon tear in bilateral shoulders, with paired human tenocyte culture experiments
Lidocaine was cytotoxic to tenocytes, reduced ultimate load to failure and stiffness, induced tenocyte apoptosis and delayed collagen organisation in a rat rotator cuff tear model.
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