Bone Marrow Mesenchymal Stem Cells Suppress Acute Lung Injury Induced by Lipopolysaccharide Through Inhibiting the TLR2, 4/NF-kappaB Pathway in Rats with Multiple Trauma.

Bone Marrow Mesenchymal Stem Cells Suppress Acute Lung Injury Induced by Lipopolysaccharide Through Inhibiting the TLR2, 4/NF-kappaB Pathway in Rats with Multiple Trauma.

Model: Multiple trauma followed by lipopolysaccharide administration to induce acute lung injury

Bone marrow mesenchymal stem cells reduced lung inflammatory injury, suppressed TLR2 and TLR4 expression and p65 phosphorylation, lowered pro-inflammatory cytokines and raised IL-10.

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