Melatonin Has An Ergogenic Effect But Does Not Prevent Inflammation and Damage In Exhaustive Exercise.
RatOtherWistarMalen = Eight groups of 15 animals, 120 rats in totalIntraperitoneal10 mg/kg30 min before the exhaustive swimming bout
Model: Exercise-induced skeletal muscle damage and inflammation from swimming to exhaustion at the individually determined anaerobic threshold intensity, in light or dark circadian periods
Melatonin was strongly ergogenic, increasing time to exhaustion (the nocturnal melatonin group swam 155.84% longer than nocturnal vehicle), but it did not prevent exercise-induced inflammation or muscle damage, and CK-MM and LDH were higher with melatonin, which the authors attributed to the longer…
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