Effects of local administration of allogenic adipose tissue-derived mesenchymal stem cells on functional recovery in experimental traumatic brain injury.
RatTBIControlled cortical impactSprague-DawleyMaleLocal intraparenchymal administration2 x 10^5 cells24 hours after controlled cortical impact
Model: Moderate unilateral controlled cortical impact
Rats given local allogeneic adipose-derived mesenchymal stem cells 24 hours after controlled cortical impact showed improved motor test performance compared with both control groups. The cells were found in perilesional tissue with numbers declining over time after transplantation, and treatment in…
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